liposomal Tea Polyphenols 70% — High Purity Green Tea Extract Supplement

Product Overview

Liposomal Tea Polyphenols 70% is a premium-grade dietary supplement ingredient delivering a full-spectrum green tea polyphenol complex in an advanced liposomal delivery system. Tea polyphenols are the predominant bioactive compounds in green tea, comprising catechins, theaflavins, flavonoid glycosides, anthocyanidins, and phenolic acids. Among these, catechins are the primary component, mainly consisting of (−)-epicatechin (EC), (−)-epicatechin-3-gallate (ECG), (−)-epigallocatechin (EGC), and (−)-epigallocatechin-3-gallate (egcg).

Tea polyphenols have been extensively studied for their antioxidant, hypoglycemic, anti-inflammatory, and antiviral effects. However, their clinical potential is limited by low stability and vulnerability to degradation due to environmental factors such as pH, temperature, oxygen, and metal ions. Liposomal encapsulation addresses this challenge by protecting tea polyphenols from degradation and enhancing their delivery to target cells.

Why Liposomal Technology?

Conventional tea polyphenols exhibit low systemic bioavailability due to rapid degradation in the gastrointestinal tract and short biological half-life. In a study using the thin film ultrasonic method, tea polyphenol-loaded liposomes (TPL) achieved an encapsulation efficiency of 92.24 ± 0.168%, with a particle size of 132.01 ± 1.053 nm and a zeta potential of −56.11 ± 4.344 mV. TPL exhibited significantly enhanced antioxidant, hypoglycemic, and antimicrobial activities compared to free tea polyphenols, and provided a sustained release profile under simulated gastrointestinal conditions.

Liposomal encapsulation provides three critical advantages:

1. Digestive Protection — The phospholipid bilayer shields tea polyphenols from enzymatic degradation and pH-dependent instability during digestive transit, preserving their intact molecular structure until reaching target cells.

2. Enhanced Cellular Uptake — Liposomes fuse directly with cell membranes, facilitating efficient cytoplasmic delivery and bypassing passive diffusion limitations. Encapsulation significantly improved the free radical scavenging ability of green tea polyphenols.

3. Sustained Release — Liposomal formulations exhibit a biphasic release profile with an initial burst release followed by sustained release, maintaining consistent particle size and encapsulation efficiency over 90 days.

Product Specifications

Key Features

• High Purity — Standardized to ≥70% total tea polyphenols by HPLC, ensuring consistent active content.

• Liposomal Delivery — Phospholipid bilayer encapsulation achieves high encapsulation efficiency and improves stability, dispersion, and cellular uptake.

• Enhanced Bioactivity — Liposomal tea polyphenols exhibit significantly enhanced antioxidant, hypoglycemic, and antimicrobial activities compared to free tea polyphenols.

• Sustained Release — Biphasic release profile provides initial burst followed by sustained release for prolonged activity.

• Water-Dispersible — Suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

For general health benefits, most studies suggest a daily intake of 250–500 mg of green tea extract standardized to contain 50–70% EGCG. A daily dose of 800 mg EGCG must not be exceeded. Exceeding 800 mg may elevate the risk of liver toxicity, so it is recommended to limit dosages to under 800 mg per day. For optimal results, green tea extracts standardized to contain 70–80% polyphenols are preferred, and it is advisable to take green tea supplements with a meal to enhance absorption.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.