Liposomal zinc citrate 80% — High Bioavailability Zinc Supplement

Product Overview

liposomal Zinc Citrate 80% is a premium-grade dietary supplement ingredient delivering zinc citrate in an advanced liposomal delivery system. Zinc citrate (CAS 546-46-3 for anhydrous; CAS 5990-32-9 for dihydrate) is an organic zinc salt formed by the complete neutralization of citric acid with a high-purity zinc source, followed by precipitation and dehydration. The dihydrate form has the chemical formula Zn₃(C₆H₅O₇)₂·2H₂O and a molecular weight of 610.37 g/mol. It is a white, odorless, crystalline powder that is practically insoluble in water but soluble in dilute mineral acids. Zinc citrate contains approximately 31% elemental zinc, one of the highest zinc contents among organic zinc salts, and is widely used as a mineral source in functional foods, beverages, dietary supplements, and oral care products.

Zinc is an essential trace mineral present in all body tissues and fluids. As a component of over 200 enzymes, it is involved in more enzymatic reactions than any other mineral, affecting virtually all aspects of the immune system and playing essential roles in hormonal functions, skin and connective tissue metabolism, and sensory perception. However, conventional zinc salts can cause gastrointestinal discomfort at effective doses, and zinc absorption is subject to tight homeostatic regulation that limits fractional absorption as doses increase.

Why Liposomal Technology?

Zinc citrate already offers superior bioavailability compared to inorganic zinc salts, and studies have shown that chelated zinc forms such as zinc citrate are better absorbed and tolerated than zinc oxide. However, conventional zinc citrate formulations still face challenges related to gastrointestinal tolerability and the saturable nature of zinc absorption.

Liposomal encapsulation provides four critical advantages:

1. Enhanced Bioavailability and Absorption — Liposomal zinc citrate is a combination of zinc citrate encapsulated in liposomes to enhance absorption and reduce gastrointestinal irritation. Liposomal encapsulation is an advanced delivery method that increases zinc absorption, intracellular uptake, and bioavailability.

2. Reduced Gastrointestinal Irritation — The liposomal form is gentle on the stomach, highly absorbable, and bioavailable, making it suitable for individuals with sensitive stomachs. Liposomal encapsulation minimizes direct contact between zinc and the gastrointestinal mucosa, reducing the risk of nausea and cramping commonly associated with conventional zinc salts.

3. Enhanced Cellular Uptake — Liposomes fuse directly with intestinal cell membranes, facilitating efficient cellular delivery via lipid-mediated pathways. Encapsulating zinc citrate in liposomes can improve its absorption and cellular uptake, making it well-suited for applications where targeted delivery and controlled release are crucial.

4. Controlled Release — Liposomal formulations provide sustained release of zinc, maintaining consistent active levels for prolonged physiological support and reducing the risk of gastrointestinal discomfort associated with immediate-release zinc supplements.

Product Specifications

Key Features

• High Purity — Standardized to ≥80% zinc citrate, with elemental zinc content of 30.0%–33.0% (USP/FCC).

• Liposomal Enhancement — Phospholipid bilayer encapsulation enhances zinc absorption, intracellular uptake, and bioavailability while reducing gastrointestinal irritation.

• Superior Bioavailability — Zinc citrate contains approximately 31% elemental zinc, one of the highest zinc contents among organic zinc salts, and offers better solubility and absorption than zinc oxide.

• Immune Function Support — Zinc supports many aspects of innate and acquired immunity and has anti-inflammatory and antioxidant effects. Clinical trial data support the value of zinc in reducing the duration and severity of symptoms of the common cold when administered within 24 hours of onset.

• Skin Health Benefits — Zinc citrate has beneficial effects for the health of hair and nails and helps heal skin wounds and skin conditions such as acne and eczema. Zinc compounds help suppress sebum secretion and reduce acne inflammation.

• Gentle on the Stomach — The liposomal form is gentle on the stomach, highly absorbable, and bioavailable, making it suitable for individuals with sensitive stomachs.

• Neutral Taste Profile — Zinc citrate has a neutral taste, unlike many other zinc salts, making it ideal for beverages and oral care applications.

• Water-Dispersible — Suitable for capsules, tablets, powder drink mixes, functional beverages, and oral care formulations.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical studies and commercial products commonly recommend 15–30 mg of elemental zinc per day from zinc citrate. A representative commercial zinc citrate supplement provides 15 mg of elemental zinc per tablet with suggested use of one tablet daily with a meal. For immune support, clinical trial protocols have used 25–40 mg daily for acute infection or immune support. For common cold support, zinc lozenges providing 10 mg of zinc from zinc citrate per lozenge are available, with research supporting administration within 24 hours of symptom onset. The Tolerable Upper Intake Level (UL) for zinc is 40 mg per day for adults. Long-term intake of 25 mg or above may lead to anaemia and copper deficiency. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.