Product Detailed Description

Liposomal lutein 40% — High Bioavailability Macular Health Supplement

Product Overview

liposomal Lutein 40% is a premium-grade dietary supplement ingredient delivering free lutein in an advanced liposomal delivery system. Lutein (CAS 127-40-2) is a naturally occurring xanthophyll carotenoid found in vegetables and fruits, and it is an important pigment that forms the macular region of the human retina. The human eye contains a high amount of lutein, which cannot be synthesized by the body and must be supplemented through dietary intake.

Lutein is a fat-soluble compound with the molecular formula C₄₀H₅₆O₂ and a molecular weight of 568.85 g/mol. It is typically extracted from the petals of marigold (Tagetes erecta L.), which is known to be the richest natural source of lutein. Lutein blocks blue light from sunlight, computer screens, and phone displays, alleviates eye fatigue, and helps prevent eye conditions such as cataracts and macular degeneration.

Why Liposomal Technology?

Conventional lutein presents significant formulation challenges. Lutein is a fat-soluble compound that is poorly soluble in water and propylene glycol, and only slightly soluble in vegetable oil and hexane. Its oral absorption is generally low, estimated at 5–20% of an oral dose, and highly variable among individuals.

Liposomal encapsulation provides three critical advantages:

1. Enhanced Solubility and Dispersibility — The use of a nano-transport system to develop active Lutein liposomes with a particle size of less than 30 nm completely solves the solubility and stability issues of lutein. This allows lutein to be stably encapsulated in nano-carriers, significantly increasing absorption efficiency and bioavailability and making the product suitable for aqueous systems.

2. Digestive Protection and Stability — Liposomal encapsulation protects lutein from degradation during digestive transit. Liposomal lutein has been shown to improve lutein stability in the in vitro simulated digestion environment, with a final retention rate of 11.52% and a 7.59-fold increase in bioaccessibility compared to free lutein.

3. Clinically Validated Superior Absorption — A liposomal lutein ingredient (LUZvision) has been clinically shown to have an absorption rate approximately 4.8 times higher than conventional lutein. A comparative pharmacokinetic study in SD rats evaluating phospholipid, liposomal, and MCT formulations demonstrated that the liposomal powder produced higher Cmax and AUC than the control (p < 0.01).

Product Specifications

Key Features

• High Purity — Standardized to ≥40% free lutein by HPLC, ensuring consistent active content.

• Liposomal Enhancement — Phospholipid bilayer encapsulation significantly enhances lutein solubility, stability, and bioavailability. Reconstituted liposomal vesicles exhibit a mean hydrodynamic diameter of 182.4 ± 4.1 nm and zeta potential of −34.7 ± 1.8 mV, indicating excellent colloidal stability.

• Clinically Validated Superior Absorption — Liposomal lutein has been clinically shown to have an absorption rate approximately 4.8 times higher than conventional lutein.

• AREDS2-Backed Ratio — Formulated with lutein and zeaxanthin in a 5:1 ratio, the optimal proportion backed by AREDS2, a major clinical trial by the National Eye Institute.

• Blue Light Protection — Lutein filters up to 90% of high-energy blue light from the visible light spectrum, protecting the retina and skin from photo-oxidative damage.

• Antioxidant Defense — Lutein is a potent antioxidant that neutralizes free radicals and reduces oxidative stress in the eyes and skin.

• Water-Dispersible — Dissolves in chilled water and remains stable during heating, storage, and processing. Suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical studies and commercial products commonly recommend 10–20 mg of free lutein per day. The AREDS2 clinical trial, a major study by the National Eye Institute, evaluated lutein (10 mg) + zeaxanthin (2 mg) supplementation and recommended adding 10 mg lutein and 2 mg zeaxanthin to the dietary supplement formula. In the AREDS2 trial, patients with the lowest baseline levels of lutein and zeaxanthin in their diets who added the supplement showed a 26% reduction in risk for AMD progression. For general eye health support, 10 mg daily is commonly used, with higher doses up to 20 mg daily used in some cognitive and skin health studies. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.