Product Detailed Description

Liposomal vitamin E Natural 20% — High Bioavailability Natural Vitamin E Supplement

Product Overview

liposomal Vitamin E Natural 20% is a premium-grade dietary supplement ingredient delivering natural-source D-alpha-tocopherol in an advanced liposomal delivery system. D-Alpha-Tocopherol (CAS 59-02-9), also known as natural vitamin E, RRR-α-tocopherol, or (2R,4'R,8'R)-α-tocopherol, is a fat-soluble antioxidant with the molecular formula C₂₉H₅₀O₂ and a molecular weight of 430.71 g/mol. The compound is chemically designated as (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol and consists of a single stereoisomer that occurs naturally in plants and human tissues. Native D-alpha-tocopherol occurs as a pale yellow to yellow, clear, viscous oil that is practically insoluble in water, freely soluble in ethanol, and miscible with fats and oils.

The 20% specification for this product represents the Active Ingredient Loading Capacity by weight relative to the total liposomal formulation. A lower percentage typically signifies a higher ratio of phospholipids for optimal stability in aqueous solutions, making the 20% concentration particularly suitable for liquid formulations, functional beverages, and applications where superior dispersion and encapsulation efficiency are prioritized. This designation allows formulators to select the optimal balance between active potency and formulation stability for their specific application.

Why Liposomal Technology?

Conventional oral vitamin E presents significant bioavailability challenges. Vitamin E is a highly lipophilic molecule that requires bile salt-mediated micelle formation for intestinal absorption, and its absorption is influenced by dietary fat intake and individual gastrointestinal conditions. Additionally, vitamin E is subject to extensive first-pass metabolism in the liver, which reduces the fraction of absorbed vitamin reaching systemic circulation.

Liposomal encapsulation provides four critical advantages:

1. Enhanced Lymphatic Absorption — A study evaluating the incorporation of α-tocopherol in marine lipid-based liposomes demonstrated that α-tocopherol recovery in lymph was increased by almost threefold following liposome administration compared to non-liposomal delivery. Liposomal formulations have demonstrated a bioavailability 3 to 5 times superior to non-liposomal forms.

2. Protection from Gastric Degradation and Oxidation — The phospholipid bilayer shields vitamin E from gastric acid and enzymatic degradation, allowing direct absorption into the lymphatic system and cells. The liposomal shell prevents oxidation of tocopherol during storage and gastrointestinal transit, enabling a sustained release for long-lasting antioxidant protection.

3. Enhanced Stability and Storage Profile — The phospholipid bilayer coat of the liposomes protects bioactives against harmful bodily processes, protecting the integrity and functionality of vitamin E. The vitamins are more stable when packed in a liposome, ensuring that vitamin E arrives in the gut in its intact form, increasing the chance of arriving at the target site in its functional form. Chitosan-coated nanoliposomes containing vitamin E demonstrated stability exceeding 90% during 8 weeks of storage at 4°C.

4. Gentle on the GI Tract and Targeted Delivery — Encapsulation minimizes direct contact with the stomach lining, significantly reducing digestive discomfort. The liposomal delivery system delivers vitamin E precisely to lipid-rich tissues and cell membranes where antioxidant defense is most needed.

Product Specifications

Key Features

• High Purity — Standardized to 20% active ingredient loading capacity by weight relative to the total liposomal formulation, ensuring a balanced ratio of phospholipid carrier for optimal stability in aqueous dispersions.

• Natural-Source Advantage — Derived from vegetable oils including sunflower, soybean, and wheat germ oil, consisting of a single stereoisomer (RRR-α-tocopherol) with higher biological activity than synthetic vitamin E.

• Liposomal Enhancement — Liposomal encapsulation significantly increases α-tocopherol recovery in lymph by almost threefold following liposome administration, yielding a bioavailability 3 to 5 times superior to non-liposomal forms.

• Potent Lipid Antioxidant — Vitamin E neutralizes reactive oxygen species (ROS) and prevents lipid peroxidation in cell membranes, protecting polyunsaturated fatty acids (PUFAs) and low-density lipoproteins (LDL) from oxidative damage.

• Cardiovascular Health Support — Vitamin E supports healthy blood vessel function and helps maintain optimal cholesterol levels through its antioxidant protection of LDL particles.

• Skin Protection — Vitamin E shields the skin from oxidative stress caused by UV radiation and environmental pollutants, supporting skin barrier integrity and reducing signs of photoaging. Liposomal vitamin E formulations have been shown to improve skin deposition and provide enhanced topical delivery.

• Cellular Longevity Support — Vitamin E enhances cellular resilience and supports healthy aging through superior biological activity and protection of cellular membranes from oxidative damage.

• Enhanced Stability — The phospholipid bilayer protects vitamin E from oxidation, with stability exceeding 90% during 8 weeks of storage at 4°C in chitosan-coated nanoliposome formulations.

• Water-Dispersible — Liposomal powder offers excellent dispersibility in aqueous systems, forming a homogeneous, translucent dispersion; suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

The Recommended Dietary Allowance (RDA) for vitamin E is 15 mg/day (22.4 IU) for adults, which is equivalent to 15 mg of α-tocopherol. The Tolerable Upper Intake Level (UL) for supplemental vitamin E is 1,000 mg/day for adults. For supplemental use, vitamin E is commonly used at 100–400 IU/day for general antioxidant support. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability and lymphatic absorption.

Important Safety Information: Vitamin E is generally well tolerated at recommended doses. High-dose vitamin E supplementation may increase the risk of bleeding, particularly in individuals taking anticoagulant or antiplatelet medications. Individuals with vitamin K deficiency or bleeding disorders should consult a healthcare professional before use. Vitamin E supplementation should be discontinued at least 2 weeks before surgery. Pregnant or lactating women and children should consult a healthcare professional before use.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.