99$/KG
89$/KG
Product Detailed Description
liposomal Magnesium L-Threonate 70% is a premium-grade dietary supplement ingredient delivering magnesium L-threonate (MgT) in an advanced liposomal delivery system. Magnesium L-threonate (CAS 778571-57-6) is a magnesium salt of L-threonic acid, a naturally occurring metabolite of vitamin C (L-ascorbic acid). The compound is chemically characterized by the molecular formula C₈H₁₄MgO₁₀ and a molecular weight of 294.5 g/mol.
Magnesium is an essential mineral involved in more than 600 biochemical reactions, contributing to normal Energy Metabolism, muscle function, nerve function, and psychological well-being. L-threonic acid serves not only as a carrier for magnesium but also as a bioactive metabolite. Magnesium L-threonate is unique among magnesium supplements in that it has been demonstrated to cross the blood-brain barrier and elevate brain magnesium levels, a property not observed with other magnesium forms such as magnesium oxide, citrate, or glycinate.
Magnesium L-threonate already offers superior bioavailability and targeted brain delivery compared to other magnesium forms. However, conventional MgT formulations still face absorption challenges related to its stability in the gastrointestinal environment and the need for efficient transport across the blood-brain barrier.
Liposomal encapsulation provides three critical advantages:
1. Digestive Protection — The phospholipid bilayer shields the magnesium-L-threonate complex from gastric acid degradation and interaction with dietary inhibitors, preserving its intact structure until reaching optimal absorption sites in the small intestine.
2. Enhanced Cellular Uptake — liposomes fuse directly with intestinal cell membranes, facilitating efficient cellular delivery via lipid-mediated pathways. This delivery mechanism complements the organic acid transport mechanisms utilized by MgT, supporting enhanced systemic absorption.
3. Synergistic Blood-Brain Barrier Delivery — Both the liposomal carrier and L-threonic acid facilitate crossing of the blood-brain barrier. This dual-route delivery system supports elevated brain magnesium concentrations, the primary mechanism by which MgT exerts its cognitive benefits.
| Field | Details |
|---|---|
| Product Name | Liposomal Magnesium L-Threonate 70% |
| CAS No. | 778571-57-6 |
| Active Ingredient | Magnesium L-Threonate (MgT) |
| Assay Method | EDTA complexometric titration or ICP-OES for elemental magnesium content; RP-HPLC with refractive index detector (RID) for L-threonic acid quantification; ICP-MS for heavy metal analysis; FTIR for chelation structure confirmation |
| Purity | ≥ 70% magnesium L-threonate; elemental magnesium ≥ 8.0% |
| Appearance / Color | White to off-white crystalline powder |
| Dosage Form | Liposomal powder, water-dispersible |
| Recommended Dosage | 1,000–2,000 mg per day; clinical trials have used 1,500–2,000 mg/day MgT |
| Application | Cognitive function, memory enhancement, synaptic plasticity, sleep quality, nervous system health, neuroprotection, mood support |
| Extract Source | Synthetic chelation (magnesium ion bound to L-threonic acid via proprietary chelation process) |
| Molecular Formula | C₈H₁₄MgO₁₀ |
| Molecular Weight | 294.5 g/mol |
| Lead Time | In stock: 3–5 business days; Bulk/custom orders: 2–3 weeks |
| Shipping Method | International Express (FedEx / DHL / UPS); air and sea freight available; worldwide shipping including remote areas |
| Storage | Cool, dry place away from direct sunlight and moisture; keep container tightly sealed. Shelf life: 24 months |
High Purity — Standardized to ≥70% magnesium L-threonate, ensuring consistent active content and ≥8.0% elemental magnesium.
Blood-Brain Barrier Penetration — Magnesium L-threonate is the only magnesium form clinically demonstrated to cross the blood-brain barrier and elevate brain magnesium levels.
Liposomal Enhancement — Phospholipid bilayer encapsulation protects the magnesium-chelate complex during digestive transit and enhances cellular delivery through lipid-mediated pathways.
Clinically Validated for Cognitive Function — Clinical studies have demonstrated that MgT supplementation improves cognitive function, sleep quality, and nervous system health.
Synaptic Plasticity Support — MgT elevates brain magnesium levels, supporting synaptic density and plasticity, the cellular basis of learning and memory.
Sleep and Recovery Support — Clinical trials have shown that MgT improves sleep depth, REM sleep, and cognitive function in athletic populations.
Water-Dispersible — Suitable for capsules, tablets, powder drink mixes, and functional beverages.
Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.
| Application | Recommended Usage | Notes |
|---|---|---|
| Capsules / Tablets | 500–1,000 mg per serving | 2–4 capsules daily with meals |
| Functional Beverages | 250–500 mg per 250 mL | Water-dispersible; suitable for RTD formats |
| Powdered Drink Mixes | 500–1,500 mg per sachet | Blend with L-theanine or phosphatidylserine for synergistic cognitive support |
| Cognitive Support Formulas | 1,000–2,000 mg per serving | Clinical trials used 1,500–2,000 mg/day |
| Sleep and Recovery Formulas | 500–1,000 mg per serving | Take in the evening to support sleep quality |
Clinical studies have evaluated magnesium L-threonate at doses ranging from 1,000 mg to 2,000 mg per day. A clinical trial evaluating MgT on sleep, recovery, and athletic performance in collegiate athletes used MgT supplementation to assess improvements in deep and REM sleep, heart rate variability, and brain recovery. Another clinical study is evaluating oral MgT supplementation for improving menopausal symptoms and quality of life among peri/post-menopausal women. For general cognitive and nervous system support, 1,000–2,000 mg daily is commonly used. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.
Stock Orders: 3–5 business days after payment confirmation.
Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.
Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.
Coverage: Worldwide shipping, including remote areas.
99$/KG
89$/KG
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