Liposomal L-Glutamine 80% — High Bioavailability Amino Acid Supplement

Product Overview

liposomal L-Glutamine 80% is a premium-grade dietary supplement ingredient delivering L-glutamine in an advanced liposomal delivery system. L-Glutamine (CAS 56-85-9), also known as 2-aminoglutaramic acid or L-2-aminoglutaramidic acid, is the most abundant free amino acid in human blood and muscle tissue . It is chemically characterized by the molecular formula C₅H₁₀N₂O₃ and a molecular weight of 146.14 g/mol. It occurs as a white crystalline powder that is soluble in water and is a member of the glutamic acid family.

L-Glutamine is a non-essential amino acid under normal physiological conditions, but becomes conditionally essential during catabolic stress such as trauma, infection, starvation, or prolonged strenuous exercise . It is synthesized from glutamic acid and ammonia and is the principal carrier of nitrogen in the body . L-Glutamine is essential for the proliferation of intestinal epithelial cells and is a critical fuel source for rapidly dividing cells including enterocytes and lymphocytes.

Why Liposomal Technology?

Conventional L-glutamine presents significant formulation challenges. The compound is rapidly metabolized in the gastrointestinal tract and is taken up extensively by enterocytes and immune cells, limiting the fraction that reaches systemic circulation. During periods of stress, blood glutamine concentrations decrease substantially, often by 20–50%, indicating increased demand and depletion .

Liposomal encapsulation provides four critical advantages:

1. Enhanced Absorption and Bioavailability — Liposomal L-glutamine powder supplements feature a liposomal delivery system from non-GMO sunflower oil containing phosphatidylcholine, designed to enhance absorption and bioavailability . Encapsulation in lipid bilayers protects L-glutamine from premature metabolism in the gastrointestinal tract.

2. Protection from Rapid Metabolism — The phospholipid bilayer shields L-glutamine from enzymatic degradation, preserving its intact structure until reaching optimal absorption sites in the small intestine.

3. Enhanced Cellular Uptake — liposomes fuse directly with intestinal cell membranes, facilitating efficient cellular delivery via lipid-mediated pathways. This delivery mechanism complements the sodium-dependent amino acid transport pathways utilized by free L-glutamine.

4. Water-Dispersible Formulation — Liposomal L-glutamine powder offers excellent dispersibility in water, forming a uniform suspension suitable for functional beverages and liquid formulations .

Product Specifications

Key Features

• High Purity — Standardized to ≥80% L-glutamine, with USP-grade assay of 98.5%–101.5% on dried basis available .

• Liposomal Enhancement — Liposomal delivery matrix from non-GMO sunflower oil containing phosphatidylcholine enhances absorption and bioavailability .

• Clinically Studied for Sickle Cell Disease — A randomized controlled study evaluated the safety and efficacy of L-glutamine in reducing the frequency of acute complications among patients with sickle cell disease .

• Gut Health Support — L-glutamine is the primary fuel source for intestinal epithelial cells and supports the integrity of the intestinal lining.

• Immune Function — L-glutamine is required for the proliferation of lymphocytes and supports immune cell function during periods of stress.

• Muscle Recovery — L-glutamine is required for the biosynthesis of nucleotides and Glutathione, making it a candidate for supporting exercise recovery .

• Water-Dispersible — Liposomal powder offers excellent dispersibility in water; suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical studies and commercial products commonly recommend 5,000 mg of L-glutamine per serving daily for adults . A clinical trial in sickle cell disease patients used L-glutamine at a dose of 0.5 g/kg/day in two divided doses . A randomized controlled study evaluated the safety and efficacy of L-glutamine in reducing the frequency of acute complications among patients with sickle cell disease . For general gut health and immune support, 5,000 mg daily is commonly used. Commercial liposomal L-glutamine powder supplements typically recommend mixing one scoop (providing 5,000 mg L-glutamine) daily with 8 ounces of water or favorite beverage .

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.