49$/KG
Product Detailed Description
Liposomal Vitamin C 80% is a premium-grade dietary supplement ingredient delivering L-ascorbic acid in an advanced liposomal delivery system. Vitamin C (L-ascorbic acid) is a water-soluble vitamin and essential nutrient for human health due to its pleiotropic functions related to its ability to donate electrons. As a cofactor, it facilitates collagen biosynthesis, carnitine and catecholamine metabolism, and enables dietary iron absorption. Vitamin C is also essential for wound healing and for the repair and maintenance of cartilage, bones, and teeth.
Humans cannot synthesize vitamin C endogenously and must acquire it through dietary intake, with fresh fruits and vegetables being the primary dietary source. The vitamin is actively taken up from the diet by intestinal sodium-dependent ascorbate transporters (SVCT1), which are saturable at higher doses. This limits the amount of vitamin C that can be absorbed from conventional oral supplements, particularly at high doses.
Vitamin C faces fundamental bioavailability limitations. The stability of vitamin C in the gastrointestinal tract restricts its absorption, and the saturable nature of SVCT1 transporters means that increasing oral doses do not proportionally increase plasma concentrations. A single 1,000 mg dose of conventional vitamin C can result in up to 80% being excreted without effective utilization by the organism.
Liposomal encapsulation provides three critical advantages:
1. Digestive Protection — High-quality liposomes act as stable carriers, encapsulating and protecting the vitamin from degradation by substances within the body‘s digestive system. This allows for efficient transport of the vitamins to the body’s cells for increased bioavailability and high absorption.
2. Enhanced Cellular Uptake — The bioavailability of vitamin C depends on limiting transport mechanisms that may be bypassed by liposome-encapsulation. Liposomes fuse directly with intestinal cell membranes, facilitating cellular delivery independent of SVCT1 transporters and providing access to intracellular compartments.
3. Clinically Validated Superior Absorption — A randomized, double-blind, placebo-controlled, crossover trial in 27 healthy adults evaluated a single 500 mg dose of placebo, standard vitamin C, and liposomal vitamin C. Liposomal vitamin C demonstrated significantly higher Cmax (plasma +27%, leukocytes +20%, p < 0.001) and AUC₀–₂₄ (plasma +21%, leukocytes +8%, p < 0.001) compared to standard vitamin C. A scoping review of 10 studies found that nine showed higher bioavailability of liposomal versus non-liposomal ascorbate: 1.2–5.4-fold higher Cmax and 1.3–7.2-fold higher AUC.
| Field | Details |
|---|---|
| Product Name | Liposomal Vitamin C 80% |
| CAS No. | 50-81-7 |
| Active Ingredient | L-Ascorbic Acid (Vitamin C) |
| Assay Method | RP-HPLC with C18 column; UV detection at 245 nm; mobile phase 0.1% metaphosphoric acid; LC-MS/MS for identity confirmation; DLS for particle size distribution; TEM for liposome vesicle structure verification |
| Purity | ≥ 80% ascorbic acid (HPLC); ≥ 95% assay available |
| Appearance / Color | White to off-white to light cream free-flowing powder |
| Dosage Form | Liposomal powder, water-dispersible |
| Recommended Dosage | 500–2,000 mg per day; clinical trials have used 500 mg single doses and 1,000 mg/5 mL formulations |
| Application | Immune support, collagen synthesis, antioxidant defense, iron absorption enhancement, skin health, cardiovascular support, cognitive function |
| Extract Source | Synthetic (Reichstein process from D-glucose); fermentation-derived grades also available |
| Molecular Formula | C₆H₈O₆ |
| Molecular Weight | 176.12 g/mol |
| Lead Time | In stock: 3–5 business days; Bulk/custom orders: 2–3 weeks |
| Shipping Method | International Express (FedEx / DHL / UPS); air and sea freight available; worldwide shipping including remote areas |
| Storage | Cool, dry place away from direct sunlight, heat, and moisture; keep container tightly sealed. Shelf life: 24 months |
High Purity — Standardized to ≥80% ascorbic acid by HPLC, ensuring consistent active content.
Liposomal Enhancement — Phospholipid bilayer encapsulation protects vitamin C from gastrointestinal degradation and enhances cellular uptake through lipid-mediated pathways, bypassing saturable SVCT1 transporters.
Clinically Validated Superior Absorption — Randomized controlled trial demonstrated 27% higher plasma Cmax and 20% higher leukocyte Cmax versus standard vitamin C.
Collagen Synthesis Support — Vitamin C is an essential cofactor for prolyl and lysyl hydroxylases, enzymes required for collagen triple-helix stabilization.
Immune Function — Vitamin C supports immune cell function and protects immune cells against oxidative stress generated during infections.
Enhanced Iron Absorption — Vitamin C reduces dietary non-heme iron to the more absorbable ferrous state and forms soluble complexes with iron in the stomach.
Water-Dispersible — Suitable for capsules, tablets, powder drink mixes, and functional beverages.
Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.
| Application | Recommended Usage | Notes |
|---|---|---|
| Capsules / Tablets | 250–500 mg per serving | 1–2 capsules daily with meals |
| Functional Beverages | 250–500 mg per 250 mL | Water-dispersible; suitable for RTD formats |
| Powdered Drink Mixes | 500–1,000 mg per sachet | Blend with vitamin D and zinc for synergistic immune support |
| Skin Health Formulas | 500–1,000 mg per serving | Clinical trial used 500 mg/day for collagen and skin benefits |
| Iron Absorption Formulas | 200–500 mg per serving | Take with iron-rich meals or iron supplements |
Clinical studies have evaluated liposomal vitamin C at doses ranging from 500 mg to 10 g. A randomized controlled trial used a single 500 mg dose of liposomal vitamin C and demonstrated significantly higher plasma and leukocyte absorption compared to standard vitamin C. Another pharmacokinetic study used a 1,000 mg/5 mL liposomal formulation with 24-hour sampling. For general immune support and antioxidant defense, 500–1,000 mg daily is commonly used. The Recommended Dietary Allowance (RDA) for adult men is 90 mg/day and for adult women is 75 mg/day, with higher requirements during illness, stress, and smoking.
Stock Orders: 3–5 business days after payment confirmation.
Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.
Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.
Coverage: Worldwide shipping, including remote areas.
49$/KG
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