Product Detailed Description

Liposomal collagen 80% — High Bioavailability Hydrolyzed Collagen Peptide Supplement

Product Overview

liposomal Collagen 80% is a premium-grade dietary supplement ingredient delivering hydrolyzed collagen peptides in an advanced liposomal delivery system. Hydrolyzed collagen, also known as collagen hydrolysate or collagen peptides, is a purified protein obtained from collagen of animals—including bovine, porcine, and marine sources—by enzymatic hydrolysis. The hydrolysis process cleaves the long triple-helical collagen chains into low-molecular-weight peptides, typically in the range of 1–5 kDa, which are water-soluble, non-gelling, and rapidly absorbed through the intestinal wall.

Collagen is characterized by a unique triple-helical conformation composed of three polypeptide chains rich in glycine, proline, and hydroxyproline. Type I collagen makes up approximately 90% of the body’s collagen and provides structural support to skin, bones, tendons, and ligaments. Type III collagen preserves elasticity in the dermis, muscles, and blood vessels. Together, Types I and III are the primary structural collagens in human skin and connective tissue.

Why Liposomal Technology?

While hydrolyzed collagen peptides already demonstrate better bioavailability than native collagen, conventional oral collagen formulations still face significant absorption limitations. Following oral ingestion, collagen peptides undergo enzymatic digestion in the gastrointestinal tract, and only a fraction reaches systemic circulation. Age-associated reductions in enzyme secretion and intestinal surface area can further reduce collagen uptake.

Liposomal encapsulation provides three critical advantages:

1. Gastric Protection — The phospholipid bilayer shields collagen peptides from premature enzymatic degradation during digestive transit, preserving their intact structure until reaching optimal absorption sites in the small intestine.

2. Enhanced Cellular Uptake — liposomes fuse directly with intestinal cell membranes, facilitating efficient cellular delivery and complementing the peptide transport pathway (PepT1) utilized by di- and tripeptides. Bioactive collagen peptides, including proline-hydroxyproline (Pro-Hyp), are transported intact across the intestinal barrier and accumulate in connective tissues.

3. Superior Clinical Efficacy — A randomized, double-blind, placebo-controlled trial in 75 healthy adults aged 25–65 years demonstrated that liposomal collagen tripeptide formulations showed an earlier onset and greater magnitude of improvement across multiple skin parameters. The liposomal formulation demonstrated a statistically significant advantage in skin elasticity at Week 8 compared with the non-liposomal formulation (p < 0.05). Notably, only the liposomal collagen tripeptide group exhibited a significant reduction in wrinkle area at Week 8 relative to placebo (p < 0.05).

Product Specifications

Key Features

• High Purity — Standardized to ≥80% hydrolyzed collagen peptide content, with ≥90% protein.

• Liposomal Enhancement — Phospholipid bilayer encapsulation protects collagen peptides from gastric degradation and enhances intestinal absorption through lipid-mediated pathways.

• Clinically Validated Skin Benefits — A randomized, double-blind, placebo-controlled trial demonstrated that liposomal collagen tripeptides significantly improved skin elasticity at Week 8 compared to non-liposomal formulations, and significantly reduced wrinkle area relative to placebo.

• Joint Health Support — A separate clinical trial using Type I and III hydrolyzed collagen peptides at 10 g/day significantly improved WOMAC scores (50.5 ± 17.0 to 33.8 ± 16.5) and AOFAS-AHFS ankle-hindfoot scores (64.2 ± 13.1 to 80.8 ± 9.9) in osteoarthritis patients over 8 weeks.

• Fibroblast Activation — Bioactive collagen peptides stimulate fibroblast proliferation and increase type I and type III procollagen mRNA levels, promoting endogenous collagen synthesis.

• Water-Dispersible — Suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical studies have evaluated collagen peptides across a range of doses. For skin health, a randomized controlled trial used 50 mL/day of a liposomal collagen tripeptide drink for 8 weeks. For joint health, a double-blind, placebo-controlled trial used 10 g/day of Type I and III hydrolyzed collagen peptides for 8 weeks in osteoarthritis patients. Commercial liposomal collagen products typically recommend 2–4 capsules daily (300 mg per capsule), providing 600–1,200 mg of liposomal collagen per day. For general skin and joint support, 2.5–5 g daily is commonly used. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.