Product Detailed Description

Liposomal calcium gluconate 80% — High Bioavailability Calcium Supplement

Product Overview

liposomal Calcium Gluconate 80% is a premium-grade dietary supplement ingredient delivering calcium gluconate in an advanced liposomal delivery system. Calcium gluconate (CAS 299-28-5) is the calcium salt of D-gluconic acid, chemically designated as D-gluconic acid, calcium salt (2:1). The anhydrous form has the molecular formula C₁₂H₂₂CaO₁₄ and a molecular weight of 430.38 g/mol, while the monohydrate form has a molecular weight of 448.39 g/mol. It occurs as white, crystalline granules or powder, is odorless, stable in air, and slowly soluble in water (1 g dissolves slowly in about 30 mL of water at 25°C and in about 5 mL of boiling water). Its solutions are neutral to litmus.

Calcium is the most abundant mineral in the human body, with approximately 99% stored in bones and teeth as hydroxyapatite complexes. The remaining 1% of "non-bone calcium" plays critical roles in muscle contraction, nerve impulse transmission, blood clotting, and hormone secretion. Calcium gluconate provides approximately 9.3% elemental calcium and is the preferred calcium salt in clinical settings for the management of hypocalcemia, including hypocalcemic tetany, hypocalcemia related to hypoparathyroidism, and hypocalcemia due to rapid growth or pregnancy.

Why Liposomal Technology?

Conventional calcium gluconate, while already well-tolerated and bioavailable, still faces limitations related to the regulated nature of intestinal calcium transport and interactions with dietary inhibitors.

Liposomal encapsulation provides four critical advantages:

1. Enhanced Bioavailability and Absorption — liposomes protect active ingredients from being destroyed by gastric acid and digestive enzymes. Due to their affinity with cell membranes, active substances can penetrate the intestinal wall more efficiently and enter the bloodstream and cells directly, with absorption rates far higher than standard powders.

2. Protection from Dietary Inhibitors — The phospholipid bilayer shields calcium from binding with oxalates or phytates in the diet, which normally block absorption.

3. Enhanced Stability and Slow Release — The phospholipid layer acts as a "protective shell," effectively preventing active ingredients from degrading due to light, oxidation, or pH changes. It also enables a slow release within the body, extending the duration of effectiveness.

4. Gentle on the Gastrointestinal Tract — Liposomal encapsulation prevents direct contact with the gastric mucosa, significantly reducing the risk of gastrointestinal discomfort and the bloating and constipation associated with traditional calcium salts.

Product Specifications

Key Features

• High Purity — Standardized to ≥80% calcium gluconate, with USP-grade purity of 98.0%–102.0% on the dried basis.

• Liposomal Enhancement — Phospholipid bilayer encapsulation protects calcium from gastric degradation and dietary inhibitors, and enhances intestinal absorption through lipid-mediated pathways.

• Superior GI Tolerance — Liposomal encapsulation prevents the "bloating" and "constipation" associated with traditional calcium carbonate or salts.

• Shielded from Inhibitors — Protects calcium from binding with oxalates or phytates in the diet, which normally block absorption.

• Optimal Bone Mineralization — Advanced delivery ensures calcium effectively reaches the bone matrix for density support.

• Nerve & Muscle Function — Efficiently replenishes calcium levels required for proper muscular contraction and neural firing.

• High Solubility — Liposomal powder offers excellent dispersibility in water compared to standard gluconate.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

The Recommended Dietary Allowance (RDA) for elemental calcium is 1,000 mg/day for adults aged 18–50 years, 1,000 mg/day for males aged 51–70 years, and 1,200 mg/day for females aged 51–70 years and all adults aged 71 years and older. Calcium gluconate can also be taken orally in tablet form, typically at a dose of 500 to 1,000 mg daily, divided into two or three doses. The Tolerable Upper Intake Level (UL) for elemental calcium is 2,500 mg/day for adults aged 19–50 years and 2,000 mg/day for adults aged 51 years and older. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.