Premium liposomal Rosehip 30% Galactolipid and Collagen Support Formula

Liposomal rosehip powder 30% — High Bioavailability Joint Comfort and Antioxidant Supplement

Product Overview

Liposomal Rosehip Powder 30% is a premium-grade dietary supplement ingredient delivering rosehip extract in an advanced liposomal delivery system. Rosehip, the fruit of Rosa canina L. (dog rose), is a rich source of polyphenols (triterpene acids, flavonoids, proanthocyanidins, catechin), essential fatty acids, galactolipid, folate, vitamin A, C and E, minerals (Ca, Mg, K, S, Si, Se, Mn and Fe), among other bioactive components. The extracts have been proven to possess antioxidant, anti-inflammatory, immunomodulation, anticancer, cardioprotective, antidiabetic, neuroprotective, and antimicrobial properties.

The key anti-inflammatory compound in rosehip is a unique galactolipid known as GOPO® ((2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-β-D-galactopyranosyl glycerol), which has been identified as the primary active ingredient responsible for the anti-inflammatory and joint-supporting benefits of rosehip. The standardized rosehip powder is designed to maximize the retention of phytochemicals, with a production process that preserves the nutrient content and is standardized to contain at least 5 mg/g of vitamin C.

Why Liposomal Technology?

Conventional rosehip extract presents significant formulation challenges. Plant-derived bioactive compounds are sensitive to degradation by UV irradiation, heat, and oxygen, and their physiological relevance depends critically on their bioaccessibility following ingestion, not merely on their measured content. Rosehip polyphenols undergo degradation during gastric transit and exhibit limited intestinal permeability due to their complex molecular structures.

Liposomal encapsulation provides four critical advantages:

1. Enhanced Stability and Protection — The results of HPLC analysis evidence the high potential for liposomal encapsulation to protect sensitive bioactives in the rosehip fruit extract from the degrading effect of UV irradiation. FTIR analysis confirmed that the plant compounds were successfully loaded within the carrier, while no chemical reaction between the rosehip fruit extract and phospholipids was detected. The rosehip-fruit-extract-encapsulated liposomes had a size of approximately 250 nm that increased to 300 nm on the seventh day of storage, while the zeta potential values were between −21 mV and −30 mV and further stabilized over 60 days of monitoring, indicating excellent physical stability.

2. Dramatically Enhanced Intestinal Permeability — In vitro release studies in simulated gastrointestinal fluids showed that the presence of enzymes and bile salts (in intestinal fluid) enhanced the rosehip-polyphenol permeability from liposomes to 70.3% after 6 hours, compared with their release in water after 24 hours and in gastric fluid after 4 hours (38.9% and 41.4%, respectively). This represents a nearly 2-fold enhancement in intestinal bioaccessibility. The obtained results indicate that the proliposome method was an effective method for rosehip fruit extract liposomal encapsulation and for the delivery of these plant-derived bioactives in foods.

3. Enhanced Cellular Uptake — Liposomal encapsulation utilizes phospholipid-based carrier technology to protect rosehip bioactives during gastrointestinal transit and facilitate enhanced intestinal absorption through membrane fusion and lipid-mediated pathways.

4. Sustained Release for Prolonged Biological Activity — Liposomal delivery provides a controlled-release profile that maintains steady plasma levels of rosehip polyphenols, supporting prolonged anti-inflammatory and antioxidant activity rather than a sharp peak followed by rapid decline.

Product Specifications

Key Features

High Purity — Standardized to ≥30% polyphenols and ≥20% flavones, with standardisation to at least 5 mg/g of vitamin C, ensuring consistent active content.

Liposomal Enhancement — Phospholipid bilayer encapsulation achieves 70.3% rosehip-polyphenol permeability in intestinal fluid after 6 hours, compared with only 41.4% in gastric fluid and 38.9% in water, representing a nearly 2-fold enhancement in intestinal bioaccessibility.

Clinically Validated for Osteoarthritis — A meta-analysis of three randomized controlled trials involving 287 patients with a median treatment period of 3 months reported that treatment with standardised rosehip powder consistently reduced pain scores, and patients allocated to rosehip powder were twice as likely to respond compared to placebo.

GMP-Compliant Production — A patented process preserves the nutrient content, harvesting fruits when fully ripe and selecting optimal fruits using laser technology. The resultant powder is standardised to contain at least 5 mg/g of vitamin C.

Anti-Inflammatory Mechanisms — Rosehip extracts demonstrate anti-inflammatory activities including reduction of pro-inflammatory cytokines and chemokines, reduction of NF-kB signalling, inhibition of pro-inflammatory enzymes including COX-1/2, 5-LOX and iNOS, reduction of C-reactive protein levels, and inhibition of pro-inflammatory metalloproteases.

Gastroprotective Advantages — In contrast to nonsteroidal anti-inflammatory drugs and aspirin, rosehip has anti-inflammatory actions that do not have ulcerogenic effects and do not inhibit platelets nor influence the coagulation cascade or fibrinolysis.

Water-Dispersible — Liposomal powder offers excellent dispersibility in aqueous systems; suitable for capsules, tablets, powder drink mixes, and functional beverages.

Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical studies and commercial products commonly recommend 2.5–5 g of rosehip powder per day. A randomized, double-blind, placebo-controlled crossover trial in 94 patients with osteoarthritis used 5 g of the herbal remedy daily for 3 months, demonstrating a significant reduction in WOMAC pain (p<0.014) compared to placebo and a significant decline in 'rescue medication' consumption (p<0.027). A meta-analysis of three randomized controlled trials involving 287 patients with a median treatment period of 3 months reported that patients allocated to rosehip powder were twice as likely to respond compared to placebo. For general joint health and antioxidant support, 2.5–5 g daily is commonly used. Commercial products typically recommend stirring 5 g (1 measuring scoop) into smoothies, juices, water, or other drinks 1–2 times a day.

Shipping & Lead Time

Stock Orders: 3–5 business days after payment confirmation.

Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

Coverage: Worldwide shipping, including remote areas.