liposomal Calcium Glycinate 80% — High Bioavailability Chelated Calcium Supplement

Product Overview

Liposomal Calcium Glycinate 80% is a premium-grade dietary supplement ingredient delivering calcium bisglycinate in an advanced liposomal delivery system. Calcium glycinate, also known as calcium bisglycinate, is a fully reacted mineral chelate in which each calcium molecule is bound to two glycine molecules through a proprietary chelation process. This structure transforms calcium into an amino acid chelate mineral that the body recognizes as a protein building block rather than an inorganic salt.

Calcium is an essential mineral required for bone and teeth structure, muscle contraction, nerve transmission, blood clotting, and cardiovascular function. However, conventional calcium supplements—particularly calcium carbonate—require stomach acid for dissociation and absorption, making them less effective for individuals with low gastric acid output and frequently causing gastrointestinal discomfort. Calcium glycinate addresses these limitations through its chelated structure and amino acid transport pathway absorption.

Why Liposomal Technology?

Calcium glycinate already offers superior bioavailability compared to inorganic calcium salts. However, liposomal encapsulation further enhances its performance through a biomimetic phospholipid bilayer that protects the mineral-chelate complex during digestive transit and facilitates efficient cellular delivery.

Liposomal encapsulation provides three critical advantages:

1. Digestive Protection — The phospholipid bilayer shields the calcium-glycine chelate from premature dissociation and interaction with dietary inhibitors, preserving its intact structure until reaching target cells.

2. Enhanced Cellular Uptake — liposomes fuse directly with intestinal cell membranes, facilitating efficient cytoplasmic delivery and complementing the amino acid transport pathway utilized by the chelate itself.

3. Thermal Stability — Liposomal calcium exhibits exceptional heat resistance. Even at 105°C for four hours—conditions that degrade most standard supplements—encapsulation efficiency remained at approximately 94.68%, close to the 94.71% measured at room temperature, with a performance drop of less than 0.5%. This thermal stability supports reliable manufacturing processes including spray drying and granulation, and ensures product integrity throughout global shipping and distribution.

Figure 2. Liposomal encapsulation protects the calcium-glycine chelate and enhances cellular delivery.

Product Specifications

Figure 3. Batch-specific COA, HPLC chromatogram, and specification sheet available.

Key Features

• High Purity — Standardized to ≥80% calcium glycinate by HPLC, ensuring consistent active content.

• Fully Chelated Structure — Each calcium molecule is bound to two glycine molecules, creating a stable ring-like chelate structure that mimics natural food nutrients.

• Superior Bioavailability — Utilizes specific amino acid transport channels for absorption, bypassing competitive pathways used by other minerals. Research indicates approximately 44% absorption compared to 22% for non-chelated forms.

• Gentle on Digestion — Does not neutralize stomach acid or cause the gas, bloating, and constipation frequently associated with calcium carbonate. Ideal for individuals with sensitive stomachs, IBS, or low gastric acid levels.

• Non-Competitive Absorption — Does not compete with iron, zinc, or magnesium for absorption and is less likely to bind with dietary inhibitors like phytates or oxalates.

• Dual-Action Relaxation — The glycine component acts as a calming neurotransmitter, offering simultaneous benefits for bone strength and sleep quality or stress reduction.

• Thermal Stability — Liposomal encapsulation maintains structural integrity under high-temperature manufacturing conditions and during global shipping.

• Water-Dispersible — Soluble in water; suitable for capsules, tablets, powder drink mixes, and functional beverages.

• Batch Traceability — Complete COA, HPLC chromatogram, FTIR identity confirmation, and calcium assay data provided for each batch.

Application & Formulation Guidance

Figure 4. Liposomal Calcium Glycinate 80% is suitable for capsules, beverages, and functional foods.

Recommended Dosage

Clinical studies and commercial products commonly recommend 300–600 mg of elemental calcium per day from calcium glycinate. A typical dosing regimen of 3 capsules daily provides approximately 331 mg of elemental calcium, covering 41% of the Nutrient Reference Value (NRV). Calcium glycinate is best taken away from meals for optimal absorption, as food can interfere with the amino acid transport pathway. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced delivery efficiency.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.