Product Detailed Description

Liposomal ferrous lactate 80% — High Bioavailability Gentle Iron Supplement

Product Overview

liposomal Ferrous Lactate 80% is a premium-grade dietary supplement ingredient delivering ferrous lactate in an advanced liposomal delivery system. Ferrous lactate (CAS 5905-52-2), also known as iron(II) lactate or iron(II) 2-hydroxypropanoate, is the ferrous salt of lactic acid. It is chemically characterized by the molecular formula C₆H₁₀FeO₆ and a molecular weight of 233.99 g/mol (anhydrous) or 288.03 g/mol (trihydrate). The compound occurs as a greenish-white powder or crystalline mass with a weak, characteristic smell and a slightly sweet taste of iron. It is easily soluble in hot water and practically insoluble in ethanol. Ferrous lactate contains approximately 19% elemental iron by weight, one of the highest iron contents among organic ferrous salts, making it a highly concentrated and efficient iron source.

Iron is an essential trace mineral required for hemoglobin synthesis, oxygen transport, electron transfer, and numerous enzymatic reactions. Ferrous lactate was designed to address the limitations of earlier iron salts that were poorly absorbed and often caused gastrointestinal discomfort. The lactate anion provides greater stability to iron by preventing its decomposition inside the intestinal tube, causing much less gastric irritation than other commonly used inorganic ferrous salts, such as ferrous sulfate.

Why Liposomal Technology?

Conventional ferrous lactate, while already offering superior gastrointestinal tolerability compared to ferrous sulfate, still faces challenges related to its relative instability in light, heat, and air, and the regulated nature of intestinal iron absorption. Ferrous lactate is easily oxidized in light, heat, and air, which can convert the ferrous (Fe²⁺) form to the less absorbable ferric (Fe³⁺) form.

Liposomal encapsulation provides four critical advantages:

1. Oxidation Protection — Ferrous lactate is easily oxidized in light, heat, and air. The phospholipid bilayer shields the ferrous iron from oxygen, light, and heat, preserving its bioactive state until reaching absorption sites.

2. Gastric Protection — The liposomal phospholipid bilayer is similar to cell membranes in the human body, which makes them progressively biocompatible. It protects the iron-lactate complex from premature interaction with gastric contents and dietary inhibitors, preserving its intact structure until reaching optimal absorption sites in the small intestine. Liposomal iron offers improved gastrointestinal absorption and bioavailability compared to conventional ferrous salts, with the free iron not chemically interacting with the gastrointestinal membrane.

3. Enhanced Cellular Uptake — liposomes fuse directly with intestinal cell membranes, facilitating efficient cellular delivery via lipid-mediated pathways. Multiple studies have demonstrated that liposomal iron achieves bioavailability comparable to or exceeding that of ferrous sulfate despite containing lower elemental iron doses. Liposomal iron is 4 times better absorbed compared to conventional iron.

4. Reduced Gastrointestinal Side Effects — Liposomal encapsulation minimizes direct contact between iron and the gastrointestinal mucosa, reducing the risk of nausea, cramping, and constipation commonly associated with conventional iron salts. Liposomal iron offers enhanced palatability and reduced gastrointestinal side effects, with dropout rates of approximately 21.6% compared to typical dropout rates of 30–50% with ferrous sulfate.

Product Specifications

Key Features

• High Purity — Standardized to ≥80% ferrous lactate, with assay not less than 96.0% on the dried basis (FCC/FAO/JECFA) and elemental iron content of 15.5%–20.0%.

• Liposomal Enhancement — Phospholipid bilayer encapsulation protects ferrous iron from oxidation in light, heat, and air, and enhances cellular delivery through lipid-mediated pathways.

• Superior GI Tolerability — The lactate anion provides greater stability to iron by preventing its decomposition inside the intestinal tube, causing much less gastric irritation than other commonly used inorganic ferrous salts, such as ferrous sulfate.

• Enhanced Bioavailability — Multiple studies have demonstrated that liposomal iron achieves bioavailability comparable to or exceeding that of ferrous sulfate despite containing lower elemental iron doses, and liposomal iron is 4 times better absorbed compared to conventional iron.

• GRAS and FDA Affirmed — Ferrous lactate is affirmed as Generally Recognized As Safe (GRAS) by the FDA under 21 CFR 184.1311 for use as a nutrient supplement and color fixative for ripe olives, with no limitation other than current good manufacturing practice.

• Excellent Stability — Ferrous lactate has the advantage of being white and more stable, and is virtually unaffected by high humidity. A distinguishing feature of lactates is their very low hygroscopicity, remaining unaffected even at high air humidity.

• Water-Dispersible — Easily soluble in hot water; suitable for capsules, tablets, powder drink mixes, functional beverages, and food fortification applications.

• Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.

Application & Formulation Guidance

Recommended Dosage

Clinical guidelines for ferrous lactate recommend the following doses: for adults, tablets: 0.2 g (2 tablets) 3 times daily; capsules: 0.15–0.3 g 3 times daily; oral liquid: 10–20 mL 3 times daily. All doses should be taken after meals. For the treatment of iron deficiency, the adult dose is 300–600 mg daily; for prevention, 200 mg daily for pregnant women. The recommended daily iron requirement is 16 mg for adults and 6 mg for infants (Japanese standard). For milk powder fortification, approximately 6 mg/100 g is used. A representative commercial ferrous lactate oral solution contains 0.1 g per 10 mL, equivalent to 19.5 mg of elemental iron, with a recommended dose of 10–20 mL 3 times daily for adults. The Tolerable Upper Intake Level (UL) for iron is 45 mg per day for adults. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.

Shipping & Lead Time

• Stock Orders: 3–5 business days after payment confirmation.

• Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.

• Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.

• Coverage: Worldwide shipping, including remote areas.