59$/KG
Product Detailed Description
liposomal Zinc Gluconate 80% is a premium-grade dietary supplement ingredient delivering zinc gluconate in an advanced liposomal delivery system. Zinc gluconate (CAS 4468-02-4), also known as zinc D-gluconate or bis(D-gluconato-O¹,O²)zinc, is an organic zinc salt formed by neutralizing gluconic acid with a high-purity zinc source followed by spray-drying. It is chemically characterized by the molecular formula C₁₂H₂₂O₁₄Zn and a molecular weight of 455.7 g/mol. The compound occurs as a white to almost white, granular or crystalline powder with good solubility in water (100 g/L) and is practically insoluble in alcohol. Zinc gluconate provides approximately 14.35% elemental zinc by weight, making it one of the most well-absorbed and well-tolerated organic zinc forms available.
Zinc is an essential trace mineral present in all body tissues and fluids. As a component of over 200 enzymes, it is involved in more enzymatic reactions than any other mineral, affecting virtually all aspects of the immune system and playing essential roles in hormonal functions, skin and connective tissue metabolism, and sensory perception. However, conventional zinc salts can cause gastrointestinal discomfort at effective doses, and zinc absorption is subject to tight homeostatic regulation that limits fractional absorption as doses increase.
Zinc gluconate already offers superior bioavailability compared to inorganic zinc salts, and studies have shown that chelated zinc forms such as zinc gluconate are better absorbed and tolerated than zinc oxide. However, conventional zinc gluconate formulations still face challenges related to gastrointestinal tolerability and the saturable nature of zinc absorption.
Liposomal encapsulation provides four critical advantages:
1. Superior Bioavailability — A randomized, controlled, four-group human clinical study in 40 metabolically healthy volunteers compared the bioavailability of 25 mg zinc in four formulations. The results demonstrated that a liquid liposomal zinc gluconate supplement achieved 2.73 times higher bioavailability than a non-liposomal zinc gluconate powder formulation. The liposomal technology (LipoSone™) effectively enhances zinc bioavailability, outperforming other supplementation forms tested.
2. Direct Mucosal Absorption — Liposomal zinc molecules are not destroyed by stomach acid, effectively isolating zinc from competitive inhibition by other nutrients in the intestine (such as calcium and iron). The nanoscale carrier (diameter controlled at 100–200 nm) mimics the structure of cell membranes, allowing zinc to directly enter the circulation through the lymphatic system, increasing absorption efficiency by 5–8 times compared to ordinary zinc salts.
3. Reduced Gastrointestinal Irritation — The liposomal form is gentle on the stomach and will not cause nausea, vomiting, or stomach discomfort even when taken on an empty stomach. The combination of zinc and gluconic acid enhances absorption and minimizes gastrointestinal irritation, making it an ideal choice for dietary supplements and fortified foods.
4. Sensory Neutralization — Liposomal technology completely locks zinc ions inside the phospholipid layer, thoroughly shielding them from metallic odor, making it widely applicable in ready-to-eat powders, oral liquids, and functional gummies.
High Purity — Standardized to ≥80% zinc gluconate, with USP-grade purity of 97.0%–102.0% on the anhydrous basis.
Liposomal Enhancement — Phospholipid bilayer encapsulation achieves 2.73 times higher bioavailability compared to non-liposomal zinc gluconate powder in human clinical study.
GRAS and FDA Affirmed — Zinc gluconate is Generally Recognized As Safe (GRAS) by the FDA under 21 CFR 182.8988 for use as a nutrient supplement, with no limitation other than current good manufacturing practice.
Immune Function Support — A double-blind, randomized, placebo-controlled clinical trial in 38 patients undergoing autologous hematopoietic stem cell transplantation demonstrated that zinc supplementation (90 mg/day zinc gluconate) significantly increased absolute lymphocyte counts (p = 0.009) and increased recent thymic emigrants at both day 30 (p = 0.008) and day 90 (p = 0.025) post-transplant, facilitating immune recovery.
Skin Health Benefits — Zinc gluconate has beneficial effects for the health of hair and nails and helps heal skin wounds and skin conditions such as acne and eczema. Zinc compounds help suppress sebum secretion and reduce acne inflammation.
Gentle on the Stomach — Liposomal zinc, when taken on an empty stomach, will not cause nausea, vomiting, or stomach discomfort.
Neutral Taste Profile — The liposomal technology completely locks zinc ions inside the phospholipid layer, thoroughly shielding them from metallic odor.
Water-Dispersible — Readily soluble in water (100 g/L); suitable for capsules, tablets, powder drink mixes, functional beverages, and oral care formulations.
Batch Traceability — Complete COA, HPLC chromatogram, and identity data provided for each batch.
| Application | Recommended Usage | Notes |
|---|---|---|
| Capsules / Tablets | 15–30 mg elemental zinc per serving | 1 capsule daily with food; avoid taking with calcium or iron supplements |
| Functional Beverages | 5–15 mg per 250 mL | Water-dispersible; neutral taste |
| Powdered Drink Mixes | 15–30 mg per sachet | Blend with vitamin C for enhanced immune support |
| Immune Support Formulas | 25–40 mg per serving | Clinical trial used 90 mg/day for immune reconstitution; 25–40 mg daily for general immune support |
| Skin Health Formulas | 15–30 mg per serving | Often combined with vitamin A, vitamin E, or biotin |
| Oral Care Products | 0.5%–2% in formulation | Antimicrobial and anti-inflammatory effects; reduces plaque and tartar formation |
Clinical studies and commercial products commonly recommend 15–30 mg of elemental zinc per day from zinc gluconate. A representative commercial zinc gluconate supplement provides 15 mg of elemental zinc per tablet with suggested use of one tablet daily with a meal. For immune support, a double-blind clinical trial used 30 mg zinc gluconate three times daily (90 mg/day) during the first 30 days post-transplant, followed by one tablet daily from day 31 to day 90. For common cold support, zinc gluconate lozenges providing 10–13 mg of elemental zinc per lozenge are available, with research supporting administration within 24 hours of symptom onset. The Tolerable Upper Intake Level (UL) for zinc is 40 mg per day for adults. Long-term intake of 25 mg or above may lead to anaemia and copper deficiency. Liposomal formulations may allow for more efficient utilization of lower doses due to enhanced bioavailability.
Stock Orders: 3–5 business days after payment confirmation.
Bulk / Custom Orders: 2–3 weeks, depending on quantity and customization requirements.
Shipping Methods: International Express (FedEx, DHL, UPS), air freight, and sea freight.
Coverage: Worldwide shipping, including remote areas.
59$/KG
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